## Abstract The synthesis of benzo[a]pyrene‐6‐^13^C is described. Perinaphthane was converted to 6‐benzoyl‐carbonyl‐^13^C‐perinaphthane which was cyclized to 2,3‐dihydrobenzo[a]pyren‐6(1H)‐one‐6‐^13^C. Subsequent reduction of the ketone followed by dehydration and dehydrogenation gave benzo[a]pyren
Synthesis of [13C6-Ring-(U)]-(±)-benzo[a]pyrene metabolites from [13C6-Ring-(U)]benzene
✍ Scribed by Bruce N. Diel; Mingcheng Han; Panna L. Kole; David B. Boaz
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- French
- Weight
- 125 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-2135
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📜 SIMILAR VOLUMES
Pure 3-l-chlorotyrosine-[ring-13 C 6 ] is prepared by chlorination of the 5-oxazolidinone of l-tyrosine-[ring-13 C 6 ] with SO 2 Cl 2 in CH 3 COOH-Et 2 O and successive one-pot regeneration of the protected aminoacidic functions by BCl 3 in dichloromethane.
## Abstract A one‐pot synthesis of (±)‐(ring ^13^C~6~)‐mandelic acid is reported. [Ring ^13^C~6~]‐benzaldehyde was cyanosilylated with trimethylsilyl cyanide (TMSCN)/Znl~2~. The resulting cyanosilylated adduct was hydrolyzed with concentrated hydrochloric acid without purification. The workup invol
6 -labeled aniline was used as a starting material for the facile synthesis of 13 C 6 -benzothiazolium salt (1).
## Abstract A four‐step procedure for the preparation of [U‐^14^C]‐1,3‐dibromobenzene and [^13^C~6~]‐1,3‐dibromobenzene, from the corresponding bromobenzene, has been developed in a 30% yield. The products were isolated in a high specific activity, 2.6 GBq/mmol, and highest possible ^13^C incorpora
## Abstract The title compound [^14^C]BAY u 3405 (1) was synthesized as part of 8‐step sequence. Starting from [U‐^14^C]aniline hydrogensulfate the final product 1 was obtained with a specific activity of 741 MBq/mmol (20 mCi/mmol) and a radiochemical purity of > 98% in an overall yield of 6 and 10