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13C labeled benzo[a]pyrenes and derivatives. 2. The synthesis of benzo[a]pyrene-6-13C

✍ Scribed by J. Ernest Simpson; Guido H. Daub; David L. Vanderjagt

Publisher: John Wiley and Sons
Year: 1980
Tongue: French
Weight: 240 KB
Volume: 17
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580170615

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✦ Synopsis

Abstract

The synthesis of benzo[a]pyrene‐6‐^13^C is described. Perinaphthane was converted to 6‐benzoyl‐carbonyl‐^13^C‐perinaphthane which was cyclized to 2,3‐dihydrobenzo[a]pyren‐6(1H)‐one‐6‐^13^C. Subsequent reduction of the ketone followed by dehydration and dehydrogenation gave benzo[a]pyrene‐6‐^13^C in 29% overall yield.

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