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Synthesis of 1-4′ -ethylphenoxy- 14C (U) -6,7 -epoxy- 3,7 -dimethyl-2 -octene. A juvenile hormone analog

✍ Scribed by J. Kalbfeld; L. J. Hoffman; J. H. Chan; D. A. Hermann

Publisher
John Wiley and Sons
Year
1973
Tongue
French
Weight
133 KB
Volume
9
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The preparation of 1‐4′ ethylphenoxy‐ ^14^C(U)‐6, 7‐ epoxy ‐ 3, 7‐dimthyl‐2‐octene (^1^, ^2^) involved a single reaction wherein 4‐ethlphenol‐^14^C(U) (^3^) was mixed with 1‐chloro‐6, 7‐epoxy‐3, 7‐dimithyl‐2‐octene in an acetone water solution at reflux lu‐sing potassium carbonate as a hydrogen chloride acceptor. Althoug this juvenile hormone analog (JHA) normally shows good shelf stabilety, the quality of the labeled material which had been purified by Colum Chromatography deterio‐rated significantly when stored neat for a period of 17 days.

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