✦ LIBER ✦

Synthesis of 1-(3,4-dimethylphenyl)-1-[ring-U-14C]phenylethane, and of 1-(3,4-dimethylphenyl)-1- phenyl[1-14C]ethane, 14C-labeled distillate of ecoscint-OTM, a biodegradable liquid scintillator

✍ Scribed by K. Saito; N. Kurihara

Publisher: John Wiley and Sons
Year: 1991
Tongue: French
Weight: 261 KB
Volume: 29
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580290310

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✦ Synopsis

Abstract

1 ‐(3,4‐Dimethylphenyl)‐ 1 ‐[ring‐U‐^14^C]phenylethane, and 1‐(3,4‐dimethylphenyl)‐ 1‐phenyl[1 ‐ ^14^C]ethane, the ^14^C‐labeled organic solvents of Ecoscint‐O^TM^, a so‐called biodegradable scintillation cocktail, were synthesized by simple two‐step reactions on a milligram scale. [Ring‐U‐^14^C]acetophenone, and [carbonyl‐^14^C]acetophenone were reduced with NaBH~4~ at the first step, then the resulting 1‐[ring‐U‐^14^C]phenylethanol, and 1‐ phenyl[1‐^14^C]ethanol were condensed with o‐xylene in the presence of H~2~SO~4~ at the second step. The radiochemical yield of the overall reaction was 16% on a scale starting with 2 mg of acetophenone, and 70% when 50 mg of acetophenone was added as a carrier.

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