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Synthesis of 14C and 3H specifically labelled 1-benzyl-4- -picolinoyl-piperazine

✍ Scribed by G. Zólyomi; Z. Budai

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
262 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Specifically labelled 1‐benzyl‐4‐picolinoyl‐piperazine (4) was synthetized for use in metabolism studies. Carbon‐14 was introduced both in benzyl and picolinoyl groups, and tritium in the benzyl group. By using commercial n‐butyllithium in n‐hexane, the yield of picolinic acid was improved.

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