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Synthesis and purification of 14C N-2-hydroxyethyl-N-nitrosourea

✍ Scribed by G. Perez; E. Possagno; G. Caponecchi; E. Lilla; C. Polcaro

Publisher
John Wiley and Sons
Year
1986
Tongue
French
Weight
185 KB
Volume
23
Category
Article
ISSN
0022-2135

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✦ Synopsis

14C N-2-hydroxyethyl-N-nitrosourea was prepared at a specific activity of 30 mCi/mmol and 1 . 2 9 mCi/mmol by a two-step synthetic sequence using 14C ethanolamine as the labelled precursor. Its puri-fication was performed by IiPLC using a Lichrosorb-DIOL column eluted by ethyl ether.The overall radiochemical yield was 10%.

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