𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Properties of PNA/DNA Chimeras

✍ Scribed by Dr. Eugen Uhlmann; Dr. David W. Will; Dr. Gerhard Breipohl; Dietrich Langner; Dr. Antonina Ryte


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
491 KB
Volume
35
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Alternate PNA-DNA chimeras (PNA-DNA)n: S
✍ Loredana Moggio; Alessandra Romanelli; Roberto Gambari; Nicoletta Bianchi; Monic πŸ“‚ Article πŸ“… 2007 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 222 KB

Peptide nucleic acids (PNAs) are oligonucleotide mimics in which the sugar-phosphate backbone has been replaced by a pseudo-peptide backbone. Among PNA-based molecules, PNA-DNA conjugates characterized by tracts of DNA bound to N and/or C terminus of PNA are very soluble in aqueous media, are able t

PNA-DNA Chimeras Forming Quadruplex Stru
✍ Veronica Esposito; Aldo Galeone; Luciano Mayol; Anna Messere; Gennaro Piccialli; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons βš– 54 KB
New synthesis of PNA–3β€²DNA linker monome
✍ Domenica Musumeci; Giovanni N. Roviello; Margherita Valente; Roberto Sapio; Carl πŸ“‚ Article πŸ“… 2004 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 112 KB

## Abstract A new synthetic strategy to get the PNA–3β€²DNA linker with the monomethoxytrityl (Mmt) group as temporary protection of the backbone to be used for the synthesis of PNA/DNA chimeras was employed and a convenient strategy to obtain Mmt PNA monomers was developed. The synthetic strategies

Targeting duplex DNA with DNA-PNA chimer
✍ L. Petraccone; E. Erra; A. Messere; D. Montesarchio; G. Piccialli; L. De Napoli; πŸ“‚ Article πŸ“… 2004 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 194 KB

## Abstract Targeting double‐stranded DNA with homopyrimidine PNAs results in strand displacement complexes PNA/DNA/PNA rather than PNA/DNA/DNA triplex structures. Not much is known about the binding properties of DNA‐PNA chimeras. A 16‐mer 5′‐DNA‐3′‐p‐(N)PNA(C) has been investigated for its abilit