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Synthesis and potential central nervous system stimulant activity of 5,8-methanoquinazolines and bornano-triazines fused with imidazole and pyrimidine

✍ Scribed by Shinichi Nagai; Takamasa Miyachi; Tetsu Nakane; Taisei Ueda; Yasuhiro Uozumi

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
32 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

Starting from 3‐chloro‐5,8‐methanoquinazoline 1 and 3‐chloro‐bornano[1,2,4]triazine 7, the novel 5,8‐methanoquinazolines 5a‐b and bornano[1,2,4]triazines 10a‐b fused with imidazole and pyrimidine were prepared. None of these compounds showed any satisfactory central nervous system stimulant activities.

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