Novel water-soluble camptothecin analogues with excellent antitumor activity have been designed and synthesized by total synthesis. The analogues were evaluated for cytotoxic activity against five tumor cell lines. The most potent analogue 6e exhibited significant antitumor activity at wider range o
โฆ LIBER โฆ
Synthesis and in vitro cytotoxicity of (RS)-20-desethyl-20-substituted camptothecin analogues
โ Scribed by Sang-sup Jew; Myoung Goo Kim; Hee-Jin Kim; Eun-Young Roh; Youn-sang Cho; Joon-Kyum Kim; Kyung-Hoe Cha; Kang-Keun Lee; Hyun-Jung Han; Heesoon Lee
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 209 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-894X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Synthesis and antitumor activity of 7-su
โ
Sang-sup Jew; Hee-Jin Kim; Myoung Goo Kim; Eun-Young Roh; Youn-sang Cho; Joon-Ky
๐
Article
๐
1996
๐
Elsevier Science
๐
English
โ 190 KB
ChemInform Abstract: Novel C-Ring Analog
โ
Duvvuri Subrahmanyam; Akella Venkateswarlu; Kalla Venkateswara Rao; Tungathurty
๐
Article
๐
2010
๐
John Wiley and Sons
โ 33 KB
๐ 2 views
## 2. Synthesis and in vitro Cytotoxicity of 5-C-Substituted 20(S)-Camptothecin Analogues. -A series of several 5-substituted camptothecin analogues [cf. (II), (IV), (VI)] are synthesized from the natural alkaloid (I) and evaluated for their in vitro anticancer activity. Some of these analogues, e
ChemInform Abstract: Synthesis and in vi
โ
S. JEW; M. G. KIM; H.-J. KIM; E.-Y. RHO; H. PARK; J.-K. KIM; H.-J. HAN; H. LEE
๐
Article
๐
2010
๐
John Wiley and Sons
โ 38 KB
๐ 2 views
ChemInform Abstract: Synthesis and in vi
โ
Sang-sup Jew; Hee-Jin Kim; Myoung Goo Kim; Eun-Young Roh; Chung Il Hong; Joon-Ky
๐
Article
๐
2010
๐
John Wiley and Sons
โ 33 KB
๐ 2 views
ChemInform Abstract: Novel C-Ring Analog
โ
Duvvuri Subrahmanyam; Vedula M. Sarma; Akella Venkateswarlu; Thungathurthi V. R.
๐
Article
๐
2010
๐
John Wiley and Sons
โ 32 KB
๐ 2 views
Synthetic studies in the alkaloid field-
โ
Mauri Lounasmaa; Pirkko Juutinen; Pekka Kairisalo
๐
Article
๐
1978
๐
Elsevier Science
๐
French
โ 380 KB