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ChemInform Abstract: Novel C-Ring Analogues of 20(S)-Camptothecin. Part 3. Synthesis and Their in Vitro Cytotoxicity of A-, B- and C-Ring Analogues.

โœ Scribed by Duvvuri Subrahmanyam; Vedula M. Sarma; Akella Venkateswarlu; Thungathurthi V. R. S. Sastry; Akella S. S. V. Srinivas; Chintakunta V. Krishna; Danvanthri S. Deevi; Sandhukhan A. Kumar; Moses J. Babu; Narayanan K. Damodaran


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel C-Ring Analog
โœ Duvvuri Subrahmanyam; Akella Venkateswarlu; Kalla Venkateswara Rao; Tungathurty ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

## 2. Synthesis and in vitro Cytotoxicity of 5-C-Substituted 20(S)-Camptothecin Analogues. -A series of several 5-substituted camptothecin analogues [cf. (II), (IV), (VI)] are synthesized from the natural alkaloid (I) and evaluated for their in vitro anticancer activity. Some of these analogues, e