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ChemInform Abstract: Synthesis of C-Ring Modified Analogues of Camptothecin.

โœ Scribed by R. YONEDA; T. KIMURA; S. HARUSAWA; T. KURIHARA

Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Novel C-Ring Analog
ChemInform Abstract: Novel C-Ring Analogues of 20(S)-Camptothecin. Part 2. Synthesis and in vitro Cytotoxicity of 5-C-Substituted 20(S)-Camptothecin Analogues.
โœ Duvvuri Subrahmanyam; Akella Venkateswarlu; Kalla Venkateswara Rao; Tungathurty ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

## 2. Synthesis and in vitro Cytotoxicity of 5-C-Substituted 20(S)-Camptothecin Analogues. -A series of several 5-substituted camptothecin analogues [cf. (II), (IV), (VI)] are synthesized from the natural alkaloid (I) and evaluated for their in vitro anticancer activity. Some of these analogues, e