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Synthesis and Evaluation of the Hydrolytical Stability of Ethyl 2-(α-Amino acid)Glycolates and Ethyl 2-(α-Amino Acid)Lactates

✍ Scribed by Jan H. L. Crommen; Etienne H. Schacht


Book ID
102774413
Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
547 KB
Volume
100
Category
Article
ISSN
0037-9646

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Heteropentapeptides containing the a-ethylated a,a-disubstituted amino acid (S)-butylethylglycine and four dimethylglycine residues, i.e., CF 3 CO-[(S)-Beg]-(Aib) 4 -OEt (4) and CF 3 CO-(Aib) 2 -[(S)-Beg]-(Aib) 2 -OEt (7), were synthesized by conventional solution methods. In the solid state, the pr