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Conformation of Peptides Containing a Chiral α-Ethylated α,α-Disubstituted α-Amino Acid: (S)-α-Ethylleucine (=(2S)-2-Amino-2-ethyl-4-methylpentanoic Acid) within Sequences of Dimethylglycine and Diethylglycine Residues

✍ Scribed by Makoto Oba; Masakazu Tanaka; Masaaki Kurihara; Hiroshi Suemune


Publisher
John Wiley and Sons
Year
2002
Tongue
German
Weight
655 KB
Volume
85
Category
Article
ISSN
0018-019X

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Conformational Study of Heteropentapepti
✍ Masakazu Tanaka; Makoto Oba; Naoto Imawaka; Yoshitsugu Tanaka; Masaaki Kurihara; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 German ⚖ 206 KB 👁 1 views

Heteropentapeptides containing the a-ethylated a,a-disubstituted amino acid (S)-butylethylglycine and four dimethylglycine residues, i.e., CF 3 CO-[(S)-Beg]-(Aib) 4 -OEt (4) and CF 3 CO-(Aib) 2 -[(S)-Beg]-(Aib) 2 -OEt (7), were synthesized by conventional solution methods. In the solid state, the pr