We have prepared three conformationally restricted analogs of DuP753 in which one of the phenyl rings in the biphenyl moiety is fused to the imidazole ring, and have investigated the conformation-biological activity relationship of these compounds. Conformational analysis on DuP753 and these compoun
Synthesis and biological evaluation of new arylthiophene analogs of DuP 753
✍ Scribed by Geneviève Estenne; Pierre Dodey; Patrice Renaut; Gérard Leclerc
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 161 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0960-894X
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✦ Synopsis
We described synthesis and biological results of analogs of DuP 753 where the central phenyl ring has been replaced by a 2,5-disubstituted thiophene.
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