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Synthesis and Biological Evaluation of Two Mannose 6-Phosphate Analogs

✍ Scribed by Sébastien Vidal; Carole Vidil; Alain Morère; Marcel Garcia; Jean-Louis Montero

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
332 KB
Volume
2000
Category
Article
ISSN
1434-193X

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✦ Synopsis

Phosphonate analogs / Mannose 6-phosphate (M6P) / Receptors / Recognition markers / Phosphonates / Natural products Two β-hydroxyphosphonate analogs of M6P have been prepared by condensation of the lithiated anion of methyldiethylphosphonate with the C-6 carbonyl of a mannose derivative. The diastereoisomers thus obtained have been separ-

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