A stereospecific synthesis of 2โฒ,3โฒ-dide
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Tai-Shun Lin; Mei-Zhen Luo; Mao-Chin Liu
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Article
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1994
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Elsevier Science
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French
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2',3'-Dideoxy-B-L-cytidine (p-L-ddC), a potent inhibitor against human hepatitis B virus (HBV) and human immunodeficiency virus (HIV), has been stexwsjwifically synthesized from Garabinose in 9 steps. Recently, 2',3'dideoxy-~D-cytidiie (ddC) has been shown to be a potent inhibitor of the replication