## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and
Synthesis 1 of Ring-Labeled L-Thyroxine-C 14
✍ Scribed by Gortatowski, Melvin J.; Kumagai, Lindy F.; West, Charles D.
- Book ID
- 126396336
- Publisher
- American Chemical Society
- Year
- 1963
- Tongue
- English
- Weight
- 420 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract A method for incorporation of a ^14^C‐label in the ring geminal methyl moiety of Vitamin A is described. The procedure involves mono methylation of 2,6‐dimethylcyclohexanone with ^14^C‐methyl iodide as catalyzed by potassium hydride to afford 2‐^14^C, 2,6‐trimethylcyclohexanone. Subsequ
## Abstract p‐Toluic acid‐ring‐^14^C was synthesized by the Friedel‐Crafts p‐carbamylation of toluene‐ring‐^14^C with N,N‐disubstituted carbamyl chloride and subsequent hydrolysis. The radiochemical yield was 61%. An attempt was made to apply this method for the synthesis of benzoic acid‐ring‐^14^C
## Abstract A synthetic procedure for C‐14‐labeled N‐methyl‐N‐nitrosoaniline is presented. Separate labeling of the methyl and phenyl side chains was achieved by using C‐14‐labeled methyl iodide and aniline, respectively. The overall yield of the four reactions was 62% and the final products were s