Synthesis of Ring C 14 -Labeled Anthranilic and 3-Hydroxyanthranilic Acid
✍ Scribed by May, Everette L.; Millican, R. Carl; Mehler, Alan H.
- Book ID
- 119961832
- Publisher
- American Chemical Society
- Year
- 1962
- Tongue
- English
- Weight
- 287 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
## Abstract The synthesis of indole‐3‐acetyl‐2‐^14^C‐N‐aspartic acid from carrier‐free indole‐3‐acetic acid‐2‐^14^C (54.5 mCi/mmole) and bis‐t‐butyl‐l‐aspartic acid was accomplished by coupling with dicyclohexylcarbodiimide followed by removal of the ester blocking groups by treatment with 2 N NaOH
## Abstract p‐Toluic acid‐ring‐^14^C was synthesized by the Friedel‐Crafts p‐carbamylation of toluene‐ring‐^14^C with N,N‐disubstituted carbamyl chloride and subsequent hydrolysis. The radiochemical yield was 61%. An attempt was made to apply this method for the synthesis of benzoic acid‐ring‐^14^C