Studies towards a postulated biomimetic Diels-Alder reaction for the synthesis of himgravine
โ Scribed by Jack E. Baldwin; Richard Chesworth; Jeremy S. Parker; Andrew T. Russell
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 224 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
A biomimetic total synthesis of bioactive tetracyclic natural product allomicrophyllone has been achieved in which a protective Diels-Alder reaction employing a disposable sacrificial 1,3-diene directs the regioselectivity of the subsequent Diels-Alder reaction.
## Abstract A tailorโmade catalytically active polymer catalyzing the bimolecular DielsโAlder reaction is described. Kinetic studies carried out in acetonitrile at 82ยฐC show a 270โfold rate acceleration (__k__~cat~/__k__~uncat~) for the DielsโAlder reaction between tetrachlorothiophene dioxide and