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Studies directed toward the synthesis of adriamycin: A diels-alder approach

✍ Scribed by T.Ross Kelly; John W. Gillard; Richard N. Goerner Jr.


Publisher
Elsevier Science
Year
1976
Tongue
French
Weight
267 KB
Volume
17
Category
Article
ISSN
0040-4039

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A second generation approach toward the synthesis of viridenomycin is described. Three key fragments of the molecule have been synthesized in stereochemically pure form. Initial studies toward the coupling of these fragments with the aim of assembling the macrocycle are detailed. Final efforts to re