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Diastereoselective intramolecular Diels-Alder reactions towards the synthesis of a taxol C-ring precursor

✍ Scribed by Laurence Grimaud; Jean-Pierre Férézou; Joëlle Prunet; Jean-Yves Lallemand


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
983 KB
Volume
53
Category
Article
ISSN
0040-4020

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Diels-Alder approach towards the stereoc
✍ J.S. Yadav; Pradip K. Sasmal 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 621 KB

An elegant stereocontrolled synthesis of a highly functionalized C ring fragment of taxol ® is d~-ribed. The route utilises a new Diels-Alder reaction followed by regioselective opening ofanhyth'ide, reductive dechlorination, Baeyer-Villiger oxidation of norbornenone system and stereodirected hydrob