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Studies on the effect of glycoprotein processing inhibitors on fusion of L6 myoblast cell lines

โœ Scribed by M.A. Spearman; J.C. Jamieson; J.A. Wright

Book ID
115892251
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
771 KB
Volume
168
Category
Article
ISSN
0014-4827

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Studies on the effect of ketoconazole on
Studies on the effect of ketoconazole on the fusion of L6 myoblasts
โœ Stephen Wayne; James C. Jamieson; Maureen A. Spearman; James A. Wright ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 687 KB

The effect of ketoconazole on the fusion of L6 myoblasts was studied. Ketoconazole was a potent inhibitor of myoblast fusion at concentrations as low as 0.1 microM, but fusion was restored when the inhibitor was removed. The inhibitor resulted in decreased binding of conA and WGA to cell surface oli