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Studies of antiproteolytic effects of glyburide on rat L6 myoblasts: Comparisons with insulin

✍ Scribed by Kenneth C. Gorray; Jonathan Maimon; Bruce S. Schneider

Book ID
116030038
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
909 KB
Volume
39
Category
Article
ISSN
1532-8600

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The effect of ketoconazole on the fusion of L6 myoblasts was studied. Ketoconazole was a potent inhibitor of myoblast fusion at concentrations as low as 0.1 microM, but fusion was restored when the inhibitor was removed. The inhibitor resulted in decreased binding of conA and WGA to cell surface oli