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Studies on the effect of mevinolin (lovastatin) and mevastatin (compactin) on the fusion of L6 myoblasts

✍ Scribed by R. S. Belo; J. C. Jamieson; J. A. Wright

Book ID
105006892
Publisher
Springer
Year
1993
Tongue
English
Weight
859 KB
Volume
126
Category
Article
ISSN
0300-8177

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Studies on the effect of ketoconazole on
Studies on the effect of ketoconazole on the fusion of L6 myoblasts
✍ Stephen Wayne; James C. Jamieson; Maureen A. Spearman; James A. Wright πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 687 KB

The effect of ketoconazole on the fusion of L6 myoblasts was studied. Ketoconazole was a potent inhibitor of myoblast fusion at concentrations as low as 0.1 microM, but fusion was restored when the inhibitor was removed. The inhibitor resulted in decreased binding of conA and WGA to cell surface oli