Effect of inhibitors of the lipoxygenase pathway on mouse myoblast fusion
โ Scribed by Sheldon Steiner; Geoffrey Manley; Thomas Adams
- Book ID
- 115891896
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 315 KB
- Volume
- 155
- Category
- Article
- ISSN
- 0014-4827
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The effect of ketoconazole on the fusion of L6 myoblasts was studied. Ketoconazole was a potent inhibitor of myoblast fusion at concentrations as low as 0.1 microM, but fusion was restored when the inhibitor was removed. The inhibitor resulted in decreased binding of conA and WGA to cell surface oli