𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Steroids. CXXXVII. 1 Synthesis of a New Class of Potent Cortical Hormones. 6α,9α-Difluoro-16α-hydroxyprednisolone and its Acetonide

✍ Scribed by Mills, J. S.; Bowers, A.; Djerassi, Carl; Ringold, H. J.


Book ID
121185187
Publisher
American Chemical Society
Year
1960
Tongue
English
Weight
816 KB
Volume
82
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Steroids CCCI (1). Radiochemical synthes
✍ D. L. Wren; J. B. Siddall; J. A. Edwards 📂 Article 📅 1967 🏛 John Wiley and Sons 🌐 French ⚖ 473 KB

## A six-step synthesis of tritiated 6a, 9a-d~uoro-l6u-methyl-11~, 17u,21 -trihydroxypregna-l,4-diene-3,20-dione (5) and 6a,9a-di~?uoro-11 f3,16a,I 7aJI -tetrahydroxypregna-I ,4-diene-3,20-dione 16~7-aeetonide ( 7 ) from the appropriate A174?9(11)-3-keto intermediates is described. Isotope inco

Steroids—CXXI synthesis of halogenated s
✍ A. Bowers; E. Denot; M.Blanca Sanchez; H.L. Ringold 📂 Article 📅 1959 🏛 Elsevier Science 🌐 French ⚖ 73 KB

## Incubation of 6u-fluoro-Reichstein's Compound 3'" (I) and its A'-analog (IV) with bovine adrenals followed by acetylation led to 6c4uorohydrocortisone acetate (II) and 6a-fluoroprednisolone acetate (III) respectively. Selenium dioxide oxidation of II also afforded III. Chromium trioxide oxidati