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A NEW CLASS OF POTENT CORTICAL HORMONES. 1 6α-CHLOROCORTICOIDS

✍ Scribed by Ringold, H. J.; Mancera, O.; Djerassi, Carl; Bowers, A.; Batres, E.; Martínez, H.; Necoechea, E.; Edwards, J.; Velasco, M.; Campillo, C. Casas; Dorfman, R. I.


Book ID
127043795
Publisher
American Chemical Society
Year
1958
Tongue
English
Weight
269 KB
Volume
80
Category
Article
ISSN
0002-7863

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Steroids—CXXI synthesis of halogenated s
✍ A. Bowers; E. Denot; M.Blanca Sanchez; H.L. Ringold 📂 Article 📅 1959 🏛 Elsevier Science 🌐 French ⚖ 73 KB

## Incubation of 6u-fluoro-Reichstein's Compound 3'" (I) and its A'-analog (IV) with bovine adrenals followed by acetylation led to 6c4uorohydrocortisone acetate (II) and 6a-fluoroprednisolone acetate (III) respectively. Selenium dioxide oxidation of II also afforded III. Chromium trioxide oxidati