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STEROIDS. CIII. 1 A NEW CLASS OF POTENT CORTICAL HORMONES, 6α-FLUOROCORTICOIDS

✍ Scribed by Bowers, A.; Ringold, H. J.


Book ID
127316184
Publisher
American Chemical Society
Year
1958
Tongue
English
Weight
285 KB
Volume
80
Category
Article
ISSN
0002-7863

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Steroids—CXXI synthesis of halogenated s
✍ A. Bowers; E. Denot; M.Blanca Sanchez; H.L. Ringold 📂 Article 📅 1959 🏛 Elsevier Science 🌐 French ⚖ 73 KB

## Incubation of 6u-fluoro-Reichstein's Compound 3'" (I) and its A'-analog (IV) with bovine adrenals followed by acetylation led to 6c4uorohydrocortisone acetate (II) and 6a-fluoroprednisolone acetate (III) respectively. Selenium dioxide oxidation of II also afforded III. Chromium trioxide oxidati