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Stereoselective synthesis of (±)-erythro- and threo-γ-hydroxynorvaline

✍ Scribed by Kenn E. Harding; Thomas H. Marman; Do-hyun Nam

Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
289 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis

Both diastereomers of racemic y-hydroxynorvaline were prepared from 4-penten-2-01 to illustrate a new general method for stereoselective synthesis of either eryrhro-or three-1,3-amino alcohol systems from a single precursor.

Non-proteinogenic y-hydroxy-a-amino acids are an important class of naturally occurring amino acids.' We

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