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ChemInform Abstract: Enantioselective Synthesis of γ-Hydroxynorvaline.

✍ Scribed by M. JACOB; M. L. ROUMESTANT; P. VIALLEFONT; J. MARTINEZ


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Enantioselective Synthesis of γ-Hydroxynorvaline.

-Key step in the synthesis of title compound (VI) is the diastereoselective alkylation of chiral Schiff base (I) with iodide ( II) obtained by ring opening of (S)-propylene oxide using Tms-I at low temperatures. -(JACOB, M.; ROUMESTANT,


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