𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Enantioselective synthesis of hydroxy α-amino acids. (-)-erythro- and (-) -threo-γ-hydroxynorvalines

✍ Scribed by Jesus Ariza; Josep Font; Rosa M. Ortuño

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
723 KB
Volume
46
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

Ihe amino acids (-)-erythro-and (-)-threo-ylqdrcqnorvaline have been synthesized fran D-ribonolactone, 6, as single chira-cursor.

Moreover, S-hydroxy-uazido-rvalerolactones 1Za and 12b have been also prepared from 6 in two different alternative ways. These compounds afford B,y-dihydroxy~~-amino acids 1Sa and 1Sb with I+ arabino and D-ribo configuration, respectively.

📜 SIMILAR VOLUMES

Stereoselective synthesis of (±)-erythro
Stereoselective synthesis of (±)-erythro- and threo-γ-hydroxynorvaline
✍ Kenn E. Harding; Thomas H. Marman; Do-hyun Nam 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 289 KB

Both diastereomers of racemic y-hydroxynorvaline were prepared from 4-penten-2-01 to illustrate a new general method for stereoselective synthesis of either eryrhro-or three-1,3-amino alcohol systems from a single precursor. Non-proteinogenic y-hydroxy-a-amino acids are an important class of natura

Diastereospecific synthesis of fungicida
Diastereospecific synthesis of fungicidal threo- and erythro- α-hydroxy aminals
✍ Johann Gasteiger; Karlheinz Kaufmann 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 202 KB

SequentiuZ reactions of 2-chZoro-or 2-bromo-3-tert-butyloxirane with p-chloropheno-2ate nnd tken uitk sodiwn triasolate Zead in two stereocontro2led ste.ps to tkreo-Triadimenol; by inverse addition of the tuo nucleophiles the erythro-isomer is obtained. l-(4-Chlorophenoxy)-3,3-dimethyl-1-(l,Z,4-tria

ChemInform Abstract: Efficient Synthesis
ChemInform Abstract: Efficient Synthesis of γ-Oxo- and γ-Hydroxy-α-amino Acids.
✍ B. MERLA; H.-J. GRUMBACH; N. RISCH 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Efficient Synthesis of γ-Oxo-and γ-Hydroxy-α-amino Acids. -Reduction of aminoester (Va) with Zn(BH 4 ) 2 permits intermediate isolation of the γ-hydroxy derivative, which is converted to lactone (IX) during silica gel chromatography. -(MERLA, B.;

Synthesis of isoquinoline alkaloids. Tot
Synthesis of isoquinoline alkaloids. Total synthesis of (±)-tetrahydroescholamine and its (±)-threo- and (±)-erythro-α-hydroxy analogs
✍ Rozwadowska, Maria D. ;Matecka, Dorota ;Brózda, Danuta 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB

## Abstract The studied tetrahydroisoquinolines 1, 2 and 3 were synthesized from a common intermediate 6, which was prepared by addition of the lithium salt of dithiane 5 to hydrastinine chloride (4).