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ChemInform Abstract: Efficient Synthesis of γ-Oxo- and γ-Hydroxy-α-amino Acids.

✍ Scribed by B. MERLA; H.-J. GRUMBACH; N. RISCH

Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

Efficient Synthesis of γ-Oxo-and γ-Hydroxy-α-amino Acids.

-Reduction of aminoester (Va) with Zn(BH 4 ) 2 permits intermediate isolation of the γ-hydroxy derivative, which is converted to lactone (IX) during silica gel chromatography. -(MERLA, B.;

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