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ChemInform Abstract: Kynureninase in Organic Synthesis: Preparation of γ-Hydroxy-α-L-amino Acids.

✍ Scribed by T. MIURA; N. MASUO; Y. FUSAMAE; T. KAJIMOTO; Y. IDA

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Kynureninase in Organic Synthesis: Preparation of γ-Hydroxy-α-Lamino Acids.

-Kynureninase catalyzes the transaldol reaction between aromatic and propargylic aldehydes and kynurenine (I). The configuration of the newly formed chiral center at the γ-position of the major isomers (III) is determined to be R.

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