ChemInform Abstract: Synthesis of α-Amino Acids Using Amino Acid γ-Anion Equivalents: Synthesis of 5-Oxo α-Amino Acids, Homophenylalanine Derivatives and Pentenylglycines.
✍ Scribed by R. F. W. JACKSON; J. L. FRASER; N. WISHART; B. PORTER; M. J. WYTHES
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 40 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
Efficient Synthesis of γ-Oxo-and γ-Hydroxy-α-amino Acids. -Reduction of aminoester (Va) with Zn(BH 4 ) 2 permits intermediate isolation of the γ-hydroxy derivative, which is converted to lactone (IX) during silica gel chromatography. -(MERLA, B.;
Facile Stereoselective Synthesis of γ-Substituted γ-Amino Acids from the Corresponding α-Amino Acids. -The mild and short procedure presented is compatible with common side-chain protecting groups, sensitive functionalities and preserves the chirality of the starting α-amino acid.
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