A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A cross metathesis and a C-glycosidation via a Mukaiyama-type aldol reaction were key features of the synthesis. The macrocyclic lactone ring was created by means of the Yamaguchi procedure.
Stereoselective formal synthesis of aspergillide A
β Scribed by Gowravaram Sabitha; D. Vasudeva Reddy; A. Senkara Rao; J.S. Yadav
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 728 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
a-Aminooxylation
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