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Solvation of acylium fragment ions in electrospray ionization quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry

✍ Scribed by Ziqiang Guan; Jerrold M. Liesch

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
330 KB
Volume
36
Category
Article
ISSN
1076-5174

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✦ Synopsis

Abstract

In electrospray ionization (ESI) quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry, certain fragment ions (e.g. acylium ions) generated either during the ion transportation process (in the source interface region) or in the ion trap are found to undergo ion–molecule reactions with ESI solvent molecules (water, acetonitrile and aliphatic alcohols) to form adduct species. These unexpected solvated fragment ions severely complicate the interpretation of mass spectrometic data. High‐resolution accurate mass measurements are important in establishing the elemental compositions of these adduct species and preventing erroneous data interpretation. Copyright © 2001 John Wiley & Sons, Ltd.

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