The solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones is described. Starting from a resin-bound protected cysteine, and employing reductive alkylation and amide formation, thiomoq~holin-3one derivatives have been synthesized through intramolecular thioether formation in good yield a
โฆ LIBER โฆ
Solid-phase synthesis of 2,3,5-trisubstituted 4H-imidazolones
โ Scribed by Udo E.W Lange
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 85 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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