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Solid-phase synthesis of 2,3,5-trisubstituted 4H-imidazolones

โœ Scribed by Udo E.W Lange


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
85 KB
Volume
43
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Solid phase synthesis of 2,4,5-trisubsti
โœ Adel Nefzi; Marc Giulianotti; Richard A. Houghten ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 170 KB

The solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones is described. Starting from a resin-bound protected cysteine, and employing reductive alkylation and amide formation, thiomoq~holin-3one derivatives have been synthesized through intramolecular thioether formation in good yield a

A traceless solid-phase synthesis of 2-i
โœ Jie-Fei Cheng; Christopher Kaiho; Mi Chen; Thomas Arrhenius; Alex Nadzan ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 98 KB

A traceless solid-phase synthesis of 2-imidazolones has been developed. Polymer-bound glycerol resin was reacted with bromoacetaldehyde diethyl acetal to give the cyclic acetal bromide on the solid support. Amination of the resin-bound acetal bromide followed by urea formation by reaction with isocy