𝔖 Bobbio Scriptorium
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Solid phase synthesis and purification of 5′-mercaptoalkylated oligonucleotides

✍ Scribed by P. Kumar; D. Bhatia; R.C. Rastogi; K.C. Gupta


Book ID
108038987
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
311 KB
Volume
6
Category
Article
ISSN
0960-894X

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A general procedure for the synthesis of branched RNA and DNA oligonucleotides has been developed. The synthetic strategy involves the 3'->5' synthesis of a DNA or RNA oligomer on a solid-phase, controlled-pore glass support with an automated DNA synthesizer. The branch point nucleoside is introduce