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SIL-TAL1 fusion gene negative impact in T-cell acute lymphoblastic leukemia outcome

✍ Scribed by Mansur, Marcela Braga; Emerenciano, Mariana; Brewer, Lilian; Sant'ana, Mariana; Mendonça, Núbia; Thuler, Luiz Claudio santos; Koifman, Sérgio; Pombo-de-Oliveira, Maria S.


Book ID
127389480
Publisher
Informa plc
Year
2009
Tongue
English
Weight
334 KB
Volume
50
Category
Article
ISSN
1042-8194

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Deregulated expression of the TAL1 gene
✍ Sylvie François; Eric Delabesse; Laurence Baranger; Marie Dautel; Charles Foussa 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB 👁 1 views

TAL1 gene deregulation is frequent in T-cell acute lymphoblastic leukemia (T-ALL) and can result from translocations involving 1p32 or, more frequently, from a cytogenetically undetectable interstitial deletion of chromosome 1. This study presents a case of T-ALL with a t(1;5)(p32;q31) involving TAL