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Short-term intensive cyclophosphamide treatment in multiple sclerosis

✍ Scribed by P. Theys; F. Gosseye-Lissoir; P. Ketelaer; H. Carton

Publisher
Springer
Year
1981
Tongue
English
Weight
609 KB
Volume
225
Category
Article
ISSN
0340-5354

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✦ Synopsis

The effect of short-term intensive cyclophosphamide therapy upon 21 patients with moderately advanced multiple sclerosis is compared with a non-treated control group of 21 patients retrospectively matched for global disability. The progression of the disease was evaluated by regular disability scoring, and the results were analyzed by non-parametric statistical tests. No significant differences in the progression of the disability could be detected during a follow-up period of 2 years.

πŸ“œ SIMILAR VOLUMES

Intensive immunosuppression with cycloph
Intensive immunosuppression with cyclophosphamide in multiple sclerosis
✍ R. E. Gonsette; L. Demonty; P. Delmotte πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 440 KB

140 MS patients were treated with intensive I.V. cyclophosphamide immunotherapy and 110 were followed over 2-4 years. Annual relapse rate incidence was calculated over a period of 2 years before and after treatment and repeated neurological scores were made during this period. The conclusions are th