Short term neurophysiological monitoring in multiple sclerosis bouts. Evaluation of steroid treatment

Short-term treatment with interferon-α/β

Short-term treatment with interferon-α/β promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis

✍ M. Kariuki Njenga; Michael J. Coenen; Nannette DeCuir; Hung-Yueh Yeh; Moses Rodr 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB 👁 1 views

The mechanisms by which type I interferons (IFN) reduce the rate and severity of exacerbations in multiple sclerosis are unknown. We utilized a model of multiple sclerosis to determine the extent of demyelination and remyelination in Theiler's murine encephalomyelitis virus (TMEV)infected SJL/J mice