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Short-term intensive cyclophosphamide treatment in progressive multiple sclerosis

✍ Scribed by G. F. Siracusa; M. P. Amato; L. Fratiglioni; D. Sità; L. Amaducci


Publisher
Springer Milan
Year
1987
Tongue
English
Weight
249 KB
Volume
8
Category
Article
ISSN
1590-1874

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Short-term intensive cyclophosphamide tr
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The effect of short-term intensive cyclophosphamide therapy upon 21 patients with moderately advanced multiple sclerosis is compared with a non-treated control group of 21 patients retrospectively matched for global disability. The progression of the disease was evaluated by regular disability scori

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140 MS patients were treated with intensive I.V. cyclophosphamide immunotherapy and 110 were followed over 2-4 years. Annual relapse rate incidence was calculated over a period of 2 years before and after treatment and repeated neurological scores were made during this period. The conclusions are th