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Long-term interferon-β treatment for multiple sclerosis

✍ Scribed by R. M. Ruggieri; N. Settipani; L. Viviano; M. Attanasio; L. Giglia; P. Almasio; V. La Bella; F. Piccoli

Publisher
Springer Milan
Year
2003
Tongue
English
Weight
70 KB
Volume
24
Category
Article
ISSN
1590-1874

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Short-term treatment with interferon-α/β
Short-term treatment with interferon-α/β promotes remyelination, whereas long-term treatment aggravates demyelination in a murine model of multiple sclerosis
✍ M. Kariuki Njenga; Michael J. Coenen; Nannette DeCuir; Hung-Yueh Yeh; Moses Rodr 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB 👁 1 views

The mechanisms by which type I interferons (IFN) reduce the rate and severity of exacerbations in multiple sclerosis are unknown. We utilized a model of multiple sclerosis to determine the extent of demyelination and remyelination in Theiler's murine encephalomyelitis virus (TMEV)infected SJL/J mice