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Sequential changes in the non-coding control region sequences of JC polyomaviruses from the cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy

✍ Scribed by Kazuo Nakamichi, Shuji Kishida, Kozue Tanaka, Akihiko Suganuma…


Book ID
120919530
Publisher
Springer Vienna
Year
2012
Tongue
English
Weight
796 KB
Volume
158
Category
Article
ISSN
1432-8798

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## Abstract The human polyomavirus JC (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system (CNS). JCV has a hyper‐variable non‐coding transcriptional control region (TCR), which contains the origin of replicati