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Identical rearranged forms of JC polyomavirus transcriptional control region in plasma and cerebrospinal fluid of acquired immunodeficiency syndrome patients with progressive multifocal leukoencephalopathy

✍ Scribed by Cesare Giovanni Fedele; Maria Rosa Ciardi; Salvatore Delia; Gerardo Contreras; José Luis Perez; Maria De Oña; Elisa Vidal; Antonio Tenorio


Book ID
111739228
Publisher
Springer US
Year
2003
Tongue
English
Weight
164 KB
Volume
9
Category
Article
ISSN
1355-0284

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## Abstract The human polyomavirus JC (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system (CNS). JCV has a hyper‐variable non‐coding transcriptional control region (TCR), which contains the origin of replicati