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High-resolution melting analysis for mutation scanning in the non-coding control region of JC polyomavirus from patients with progressive multifocal leukoencephalopathy

✍ Scribed by Nakamichi, Kazuo; Tajima, Shigeru; Lim, Chang-Kweng; Saijo, Masayuki

Book ID: 121512566
Publisher: Springer Vienna
Year: 2014
Tongue: English
Weight: 681 KB
Volume: 159
Category: Article
ISSN: 1432-8798
DOI: 10.1007/s00705-014-1988-4

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## Abstract The human polyomavirus JC (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system (CNS). JCV has a hyper‐variable non‐coding transcriptional control region (TCR), which contains the origin of replicati