The clinical significance of p53 gene mu
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Hiroshi Hayashi; Kenji Sugio; Takashi Matsumata; Eisuke Adachi; Kenji Takenaka;
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Article
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1995
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John Wiley and Sons
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English
โ 639 KB
To clarify the clinical significance of the mutation of p53 gene in hepatocellular carcinoma (HCC), 90 resected specimens from Japanese patients were assayed using a polymerase chain reaction-single strand conformation polymorphism (PCRSSCP) analysis. p53 mutations were detected in 25 cases (27.8%)