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Identification of G to T transversion at codon 157 in p53 gene of human ovarian carcinoma

โœ Scribed by Fuad Fares; Limor Monadeev; Haim Avramovitz; Miriam David


Book ID
116434582
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
165 KB
Volume
130
Category
Article
ISSN
0301-2115

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This study was conducted to evaluate the frequency and prognostic impact of TP53 alterations stratified for the TP53 codon 72 polymorphism (c.215G4C, p.Arg72Pro) in a cohort of 109 patients with advanced ovarian carcinomas. TP53 sequence variants were observed in 80 of the 109 (73.4%) tumors and wer