๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Reduction of first-pass metabolism of propranolol after oral administration of ester prodrugs

โœ Scribed by Anderson, B.D.; Chu, W.W.; Galinsky, R.E.


Book ID
125418421
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
318 KB
Volume
43
Category
Article
ISSN
0378-5173

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Effect of oral ketoconazole on first-pas
โœ Masanori Kuroha; Hideki Kayaba; Shizuka Kishimoto; Waleed F. Khalil; Minoru Shim ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 84 KB

The long-term oral ketoconazole (KTZ) treatment extensively inhibits hepatic CYP3A activity. We investigated the effect of the KTZ treatment on hepatic and intestinal extraction of nifedipine (NIF) using beagle dogs. Four dogs were given orally KTZ for 20 days (200 mg, bid). NIF was administered eit