𝔖 Bobbio Scriptorium
✦   LIBER   ✦

RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis

✍ Scribed by Di Fiore, Riccardo; D'Anneo, Antonella; Tesoriere, Giovanni; Vento, Renza


Book ID
120080534
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
845 KB
Volume
228
Category
Article
ISSN
0021-9541

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


RB1CC1 activates the promoter and expres
✍ Kaichiro Ikebuchi; Tokuhiro Chano; Yasuko Ochi; Hitosuke Tameno; Taketoshi Shima πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 416 KB

## Abstract __RB1__‐inducible coiled‐coil 1 (RB1CC1, also known as FIP200) is a tumor suppressor implicated in the regulation of RB1 (retinoblastoma 1) expression. However, the molecular mechanism of RB1 regulation by RB1CC1 has not been elucidated. Here, we demonstrate that nuclear RB1CC1 binds to

Loss of heterozygosity and mutations are
✍ Kwong Wai Choy; Chi Pui Pang; Christopher B.O. Yu; Hing Lok Wong; Joan S.K. Ng; πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 80 KB πŸ‘ 2 views

We investigated sequence alternation, promoter methylation, and loss of heterozygosity (LOH) of the RB1 gene as possible mechanisms of its inactivation in retinoblastoma. In 42 Chinese patients with sporadic retinoblastoma, the promoter and entire coding region of RB1 were examined for sequence chan